Hepatoprotective: Emblica officinalis is a constituent of many hepatoprotective formulations available in market. 50% alcoholic extract of Emblica officinalis and quercetin isolated from it produced significant hepatoprotection against country made liquor (CML) and paracetamol challenge in albino rats and mice respectively.
Another study revealed that both the aqueous fruit extract and ascorbic acid could prevent the toxic effects induced by both metals Pb(NO3)2 or Al2(SO4)3.18H2O, but the extract was more effective than ascorbic acid alone.
Hypolipidemic: Emblica officinalis juice is an effective hypolipidemic agent and can be used as a pharmaceutical tool in hyperlipidemic subjects.
Feeding of Amla to the hypercholesterolemic rabbits for 12 weeks showed a two pronged effects, its feeding increased the lipid mobilization and catabolism and retarded the deposition of lipids in the extra hepatic tissues. The degree of atherosclerosis at the end of 12 weeks of Amla feeding was much lower when compared to the control group.
The tissue lipid levels including Serum cholesterol, TG, phospholipid and LDL showed a significant reduction following Emblica officinalis juice administration. Emblica officinalis juice treated rabbits excreted more cholesterol and phospholipids, suggesting that the mode of absorption was affected.
Anticlastogenic: A crude aqueous extract from the Emblica officinalis fruit following orally administration, exhibited significant protective action against damage induced by CsCl.
Antacid: Clinical studies were conducted to investigate the effect of Emblica officinalis in amlapitta (gastritis syndrome). The drug was found to be effective in 85 per cent of cases.
Cases of hyperchlorhydria with burning sensation in abdominal and cardiac regions and epigastric pain were also benefited with Emblica officinalis.
Dyspepsia: The therapeutic efficacy of Amalaki in cases of dyspepsia was evaluated and the results clearly indicate the efficacy of Emblica officinalis, in relieving the dyspeptic symptoms as well as in promoting ulcer healing.
Anticancer: Emblica officinalis, an excellent source of vitamin C (ascorbate) when administered orally, has been found to enhance natural killer (NK) cell activity and antibody dependent cellular cytotoxicity (ADCC) in syngeneic BALB/c mice, bearing Dalton's lymphoma ascites (DLA) tumor. An increase in life span (ILS) of 35% was recorded in tumor bearing mice treated with Emblica officinalis. These results indicated
a) An absolute requirement for a functional NK cell or K cell population in order that Emblica officinalis can exert its effect on tumor bearing animals, and
b) The antitumor activity of Emblica officinalis is mediated primarily through the ability of the drug to augment natural cell mediated cytotoxicity.
In Kamasutra (The ancient Indian text book of Sex and Health,written in probably 2nd century AD) there are so many herbal parts described in the context of retaining sex-power and the first of them is the Amla.
Emblica officinalis. The first of these is an ancient herb called amla (Emblica). The Kama Sutra says that if a man uses the extract of amla, he will make women desire him. Although this may seem dramatic, the Indian herbal tradition supports the notion that amla can be a powerful sex tonic.
Indian herbal masters believed that the decrease in sexual desire that a man begins to experience in middle age was due to increased stress. Stress, in turn, was believed to cause a decrease in the essential nutrients in the body that promote a healthy sex life. Therefore, Indian herbal masters turned to amla, a pulverized fruit extract rich in dozens of essential nutrients, to revitalize sexual health.
At the University of Delhi and the University of Rajasthan in India, two separate studies revealed that amla also seems to help maintain healthy cholesterol levels (Jacob 1988; Mathur 1996). Cholesterol can be a significant enemy of sexual health, because it can impede the all-important flow of blood to the genitals. Researchers therefore suggest that by maintaining healthy cholesterol, amla can support blood flow.
A study conducted at the Department of Foods & Nutrition, Lady Irwin College, University of Delhi, New Delhi, India has demonstrated that the Indian Gooseberry (amla-Emblica officinalis, Gaertn.) can reduce high serum cholesterol levels. The effect on total serum cholesterol and its lipo-protein fractions of supplementation of the diet with the Indian gooseberry was studied in normal and hypercholesterolaemic men aged 35-55 years. The fresh gooseberry was eaten(un-cooked) for a period of 28 days. Both normal and hypercholesterolaemic participants showed a decrease in cholesterol levels. However, two weeks after withdrawing the supplement, the total serum cholesterol levels of the hypercholesterolaemic subjects rose significantly almost to initial levels.